DocumentCode
3217748
Title
Deterministic Boolean networks (DBN) modeling of molecular biology: DNA replication
Author
Yeol, Joe W. ; Samarrai, W. ; Barjis, I. ; Ryu, Y.S.
Author_Institution
Dept. of Mech., Aerosp., & Manuf. Eng., Polytech. Univ. Brooklyn, NY, USA
fYear
2005
fDate
2-3 April 2005
Firstpage
120
Lastpage
122
Abstract
In this paper, we introduce a new method of modeling tool for a biological process -central dogma. The deterministic Boolean Network (DBN) is used as a modeling tool of the whole process, which enables us to simulate, analyze, and manipulate (in the future) at our disposal. From DNA to protein via RNA is the one of most well-known biological process, sometimes called central-dogma. Most of biological processes are deterministic and ruled by very precise commands, including control directions. These two common facts tell that it is the key in understanding biological processes to represent and analyze the flow of data of biology. As a result, the modeled process is easy to understand and to be implemented as a simulator to make students understood in classes; analyze and predict the process for researchers in near future.
Keywords
Boolean functions; DNA; biochemistry; cellular biophysics; genetics; molecular biophysics; proteins; DNA replication; RNA; biological process; central dogma; deterministic Boolean network; molecular biology modeling; protein; Analytical models; Biological processes; Biological system modeling; Computational biology; DNA; Predictive models; Production; Proteins; RNA; Systems biology;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioengineering Conference, 2005. Proceedings of the IEEE 31st Annual Northeast
Print_ISBN
0-7803-9105-5
Electronic_ISBN
0-7803-9106-3
Type
conf
DOI
10.1109/NEBC.2005.1431954
Filename
1431954
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