• DocumentCode
    3217748
  • Title

    Deterministic Boolean networks (DBN) modeling of molecular biology: DNA replication

  • Author

    Yeol, Joe W. ; Samarrai, W. ; Barjis, I. ; Ryu, Y.S.

  • Author_Institution
    Dept. of Mech., Aerosp., & Manuf. Eng., Polytech. Univ. Brooklyn, NY, USA
  • fYear
    2005
  • fDate
    2-3 April 2005
  • Firstpage
    120
  • Lastpage
    122
  • Abstract
    In this paper, we introduce a new method of modeling tool for a biological process -central dogma. The deterministic Boolean Network (DBN) is used as a modeling tool of the whole process, which enables us to simulate, analyze, and manipulate (in the future) at our disposal. From DNA to protein via RNA is the one of most well-known biological process, sometimes called central-dogma. Most of biological processes are deterministic and ruled by very precise commands, including control directions. These two common facts tell that it is the key in understanding biological processes to represent and analyze the flow of data of biology. As a result, the modeled process is easy to understand and to be implemented as a simulator to make students understood in classes; analyze and predict the process for researchers in near future.
  • Keywords
    Boolean functions; DNA; biochemistry; cellular biophysics; genetics; molecular biophysics; proteins; DNA replication; RNA; biological process; central dogma; deterministic Boolean network; molecular biology modeling; protein; Analytical models; Biological processes; Biological system modeling; Computational biology; DNA; Predictive models; Production; Proteins; RNA; Systems biology;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioengineering Conference, 2005. Proceedings of the IEEE 31st Annual Northeast
  • Print_ISBN
    0-7803-9105-5
  • Electronic_ISBN
    0-7803-9106-3
  • Type

    conf

  • DOI
    10.1109/NEBC.2005.1431954
  • Filename
    1431954