Image-guided multiscale statistical model to mimic random bone structure

A multiscale voxel modeling approach was presented to model the bone structure both in macroscopic and microscopic level. Based on the digital image, the overall macroscopic geometry of the vertebrate was acquired by traditional reverse engineering technology and the microscopic random trabecular network was described by two-point correlation function and the function was then used to reconstruct the bone microstructure. It was shown that the reconstructed model is statistically equivalent to the original structure in the microscopic level and has the overall feature as original bone.