The encapsulation of curcumin in micelles

This report demonstrates the preparation of a curcumin-encapsulated microemulsion system by using biocompatible materials. In this study, ethyl oleate, lecithin and Tween80 were chosen as the oil phase and surfactants, respectively. The result indicated that when the mole ratio of Lecithin/Tween 80 was 0.3, the optimum capacity of oil solubility would reach 10.3% by weight. We also performed an in-vitro analysis for testing the stability of this microemulsion. Three days after diluted with deionized water, no aggregation or leakage were observed in the microemulsion system. These studies might be valuable for the development of microemulsion formulation in pharmaceutical industry.