Integrated microfabricated devices for genetic assays

Author

Mastrangelo, C.H. ; Burns, M.A. ; Burke, D.T.

Author_Institution

Dept. of Electr. Eng. & Comput. Sci., Michigan Univ., Ann Arbor, MI, USA

fYear

1999

fDate

6-8 July 1999

Firstpage

58

Lastpage

59

Abstract

Genetic assays are powerful technology drivers and excellent candidate applications for miniaturization technologies because the demand for inexpensive genetic information is essentially unlimited, and the cost and time for the assay decrease with sample volume. Genetic information is stored in long DNA molecules in solution. Processing of DNA molecules in the microscale hence requires the implementation of microfluidic devices capable of handling, mixing, thermal cycling, separating, and detecting nano and pico liter liquid samples. This paper discusses the implementation of integrated microfluidic devices for DNA processing.

Keywords

DNA; biological techniques; biosensors; microfluidics; microsensors; mixing; DNA processing; cost; genetic assays; genetic information; integrated microfabricated devices; integrated microfluidic devices; long DNA molecules; microfluidic devices; miniaturization technologies; mixing; nano liter liquid samples; pico liter liquid samples; thermal cycling; Biochemistry; Chemical analysis; DNA; Diseases; Fluorescence; Genetics; Humans; Microfluidics; Polymers; Testing;

fLanguage

English

Publisher

ieee

Conference_Titel

Microprocesses and Nanotechnology Conference, 1999. Digest of Papers. Microprocesses and Nanotechnology '99. 1999 International

Conference_Location

Yokohama, Japan

Print_ISBN

4-930813-97-2

Type

conf

DOI

10.1109/IMNC.1999.797475

Filename

797475