Monitoring of adenosine within hollow core photonic crystal fiber by surface enhanced Raman scattering (SERS)

Hollow core photonic crystal fiber (HC-PCF) has emerged as a new generation micro-structured fibers with an ability to confine light within the core region. The possibility of infiltrating the analyte within the HC-PCF has further given boost to the strong light-matter interaction. It, therefore, lays a platform for harnessing the maximum potential of existing spectroscopic techniques in sensing broad range of molecules. The presented work aims to utilize one such technique known as surface enhanced Raman scattering (SERS) in conjugation with HC-PCF for monitoring adenosine in presence of nano structured materials. The novelty of the presented work primarily lies in realizing the SERS signal of adenosine molecule by non-selectively filling all the holes of HC-PCF while exploiting the bandgap property of HC-PCF. Such detection scheme facilitates enhancement in Raman signal by nano materials and HC-PCF. Additionally, an effort has been made to measure the actual contribution of enhancement by HC-PCF from that of nanoparticles in the overall Raman signal enhancement of adenosine.