DocumentCode
3231674
Title
The Mathematical Theory of Integrative Physiology: Application to hippocampus for drug discovery
Author
Bennani, Omar ; Chauvet, Pierre ; Dupont, Jean-Marc
Author_Institution
CHArt, Ecole Pratique des Hautes Etudes, Paris, France
fYear
2010
fDate
23-26 Sept. 2010
Firstpage
1406
Lastpage
1416
Abstract
The modeling and the simulation of biological structure needs a united formalism for all parts of a living system. For this purpose the MTIP (Mathematical Theory of Integrative Physiology) has been developed, by Pr Gilbert Chauvet, to offer an integrated description of a living system. In this paper we will present mainly the passage from a mathematical view of a living subsystem (CA1 circuit of the hippocampus) to its computational implementation and the development of the simulator that goes with in the aim to use and validate the MTIP.
Keywords
mathematical analysis; pharmaceutical industry; physiological models; CA1 circuit hippocampus; Mathematical Theory of Integrative Physiology; drug discovery; hippocampus; integrative physiology; mathematical theory; Biological system modeling; CA1 circuit; Computing system; Hippocampus; MTIP;
fLanguage
English
Publisher
ieee
Conference_Titel
Bio-Inspired Computing: Theories and Applications (BIC-TA), 2010 IEEE Fifth International Conference on
Conference_Location
Changsha
Print_ISBN
978-1-4244-6437-1
Type
conf
DOI
10.1109/BICTA.2010.5645287
Filename
5645287
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