• DocumentCode
    3246317
  • Title

    Contactless characterization of yeast cell cultivation at 7 GHz and 240 GHz

  • Author

    Wessel, Jan ; Schmalz, K. ; Cahill, B.P. ; Gastrock, G. ; Meliani, Chafik

  • Author_Institution
    IHP, Frankfurt (Oder), Germany
  • fYear
    2013
  • fDate
    20-23 Jan. 2013
  • Firstpage
    70
  • Lastpage
    72
  • Abstract
    Experimental results of contactless and label-free characterization techniques of cell cultivation are presented. The two demonstrated approaches are compared at two frequencies, 7 GHz and 240 GHz in terms of sensitivity and applicability. At 7 GHz, measurements have been performed using a rat-race based characterizing system. Furthermore, the sensitivity of spectroscopy measurements at 240 GHz has been compared for two extracted parameters: phase and amplitude. The conducted experiments demonstrate that by selecting the proper characterization parameter, the presented techniques are suitable for cell cultivation monitoring in a pipe based microfluidic system with PTFE tubes. Especially, the use of higher frequencies enables a higher compactness.
  • Keywords
    bioMEMS; biosensors; cellular biophysics; high-frequency effects; microfluidics; microorganisms; microwave spectra; sensitivity; PTFE tubes; biosensors; contactless characterization; frequency 240 GHz; frequency 7 GHz; label-free characterization techniques; parameter extraction; pipe based microfluidic system; rat-race based characterizing system; sensitivity; spectroscopy measurements; yeast cell cultivation monitoring; Biosensors; Microfluidics; Microwave measurement; Microwave theory and techniques; Permittivity; Photoconductivity; Sugar; biosensor; label-free; microfluidic; microwave; permittivity; sub-THz;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Biomedical Wireless Technologies, Networks, and Sensing Systems (BioWireleSS), 2013 IEEE Topical Conference on
  • Conference_Location
    Austin, TX
  • Print_ISBN
    978-1-4673-2930-9
  • Type

    conf

  • DOI
    10.1109/BioWireleSS.2013.6613678
  • Filename
    6613678