DocumentCode :
3249259
Title :
Synaptic dynamics influence the phase of a neural response
Author :
Graham, Bruce P.
Author_Institution :
Sch. of Natural Sci., Univ. of Stirling, Stirling, UK
fYear :
2011
fDate :
6-9 Dec. 2011
Firstpage :
79
Lastpage :
84
Abstract :
The postsynaptic response of a neuron to time-varying inputs is determined by the interaction of presynaptic spike times with the short-term dynamics of each synapse. Such synaptic dynamics makes the postsynaptic neuron more sensitive to input rate fluctuations than to average firing rates. Here we show that the postsynaptic neural spiking response to a rhythmically frequency-modulated population input can exhibit a predictive phase lead due to depressing synapses. The magnitude of the lead increases with increasing correlations between the input spike trains. Facilitation and vesicle recycling rates also influence the phase.
Keywords :
bioelectric phenomena; brain; cellular biophysics; digital simulation; medical computing; neural nets; neurophysiology; depressing synapses; firing rate; input rate fluctuation; input spike train; neural response; postsynaptic neural spiking response; postsynaptic response; presynaptic spike time; rhythmically frequency-modulated population input; synapse short-term dynamics; time-varying input; vesicle recycling rate; Frequency modulation; Histograms; Lead; Neurons; Phase modulation; Time frequency analysis;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Intelligent Sensors, Sensor Networks and Information Processing (ISSNIP), 2011 Seventh International Conference on
Conference_Location :
Adelaide, SA
Print_ISBN :
978-1-4577-0675-2
Type :
conf
DOI :
10.1109/ISSNIP.2011.6146550
Filename :
6146550
Link To Document :
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