Title :
Deformability and viscoelasticity of diabetic erythrocytes measured by microchannel flow system and atomic force microscope
Author :
Minamitani, Haruyuki ; Kawamura, Tomomi ; Sekizuka, Eiichi ; Simizu, Tomoya ; Tsukada, Kousuke ; Oshio, Chikara
Author_Institution :
Keio Univ., Yokohama, Japan
Abstract :
Mechanical properties of erythrocytes under diabetic and some other conditions were measured by using transparent micro-channel flow system and atomic force microscope (AFM). Deformability and viscoelasticity of erythrocytes were well correlated both in the healthy control and diabetes mellitus in which the hardness of erythrocytes may affect on the growth of microangiopathy
Keywords :
atomic force microscopy; biological techniques; blood; blood flow measurement; cellular transport; diseases; haemorheology; atomic force microscope; deformability; diabetes mellitus; diabetic erythrocytes; growth; hardness; healthy control; mechanical properties; microangiopathy; microchannel flow system; transparent micro-channel flow system; viscoelasticity; Atomic force microscopy; Atomic measurements; Diabetes; Elasticity; Fluid flow measurement; Force measurement; Mechanical factors; Microchannel; Springs; Viscosity;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802107
