Electrical characterization of a pig odorant binding protein by Impedance Spectroscopy

Author

Capone, S. ; De Pascali, C. ; Francioso, L. ; Siciliano, P. ; Persaud, K.C. ; Pisanelli, A.M.

Author_Institution

Inst. for Microelectron. & Microsyst., CNR, Lecce, Italy

fYear

2009

fDate

25-28 Oct. 2009

Firstpage

1758

Lastpage

1762

Abstract

In this work, an ab-initio study of the electrical response to odorants of a self-assembled monolayer of a pig OBP immobilized onto a miniaturized Si-substrate equipped with gold interdigitated electrodes (IDE), was started. Electrical impedance spectroscopy (EIS) was used as electrical characterization technique and a dedicated experimental set-up was arranged in order to carry out EIS measurements in controlled environment. The EIS data was fitted by using a fitting software based on Levenberg-Marquardt (LEVM) algorithm to determine the equivalent circuit of the system.

Keywords

ab initio calculations; biological techniques; chemioception; curve fitting; electrochemical analysis; electrochemical electrodes; electrochemical impedance spectroscopy; equivalent circuits; gold; molecular biophysics; monolayers; proteins; self-assembly; Au; EIS; Levenberg-Marquardt algorithm; Si; ab-initio study; electrical impedance spectroscopy; electrical response; equivalent circuit; gold interdigitated electrodes; miniaturised silicon substrate; pig OBP electrical characterization; pig OBP self assembled monolayer; pig odorant binding protein; Animals; Biomimetics; Electrochemical impedance spectroscopy; Electrodes; Gas detectors; Gold; Insects; Microelectronics; Olfactory; Proteins;

fLanguage

English

Publisher

ieee

Conference_Titel

Sensors, 2009 IEEE

Conference_Location

Christchurch

ISSN

1930-0395

Print_ISBN

978-1-4244-4548-6

Electronic_ISBN

1930-0395

Type

conf

DOI

10.1109/ICSENS.2009.5398471

Filename

5398471