Title :
Force development model of skeletal muscles, using Erlang loss system
Author :
Yokota, M. ; Yokota, Y.
Author_Institution :
Nagoya Bunri Univ., Aichi, Japan
Abstract :
The force development mechanism, which is composed of two stages-(1) Ca2+ was bound to binding sites on troponin molecule and (2) myosin heads binding ATP in skeletal muscles, was investigated by applying stochastic Erlang loss system. As for (1), the affinities between Ca2+ and binding sites were estimated for each slow and fast muscle fibers, and as for (2), the frequency of myosin heads binding ATP (or ADP) was examined
Keywords :
binding energy; biomechanics; molecular biophysics; muscle; physiological models; queueing theory; stochastic processes; stochastic systems; Ca2+ release; Poisson distribution; binding sites; fast muscle fibers; force development model; muscle activation; myosin heads binding ATP; queueing process; skeletal muscles; slow muscle fibers; stochastic Erlang loss system; troponin molecule; Acceleration; Biochemistry; Calcium; Exponential distribution; Frequency estimation; Kinetic theory; Magnesium; Muscles; Poisson equations; Stochastic systems;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.802628
