Effect of randoms on signal-to-noise-ratio in TOF PET

Author

Conti, Maurizio

Author_Institution

Molecular Imaging, Siemens Med. Solution, Knoxville, TN, USA

Volume

3

fYear

2005

fDate

23-29 Oct. 2005

Abstract

Time-of-flight (TOF) positron emission tomography (PET) has the potential to improve signal-to-noise ratio. In the literature, this improvement has been estimated as proportional to the square root of D/Δx, where D is the radial dimension of the object to be imaged, and Δx is the spatial uncertainty associated with the time resolution of the scanner. This estimate does not include the effect of the randoms. In this paper we discuss the role of random coincidence in TOF PET; in particular, the improvement in signal-to-noise-ratio (SNR) due to random reduction in TOF PET. We introduce and discuss a simple model for this improvement, modify the traditional estimate for SNR gain, and compare it to experimental data from a Siemens Hi-Rez PET scanner with TOF capability.

Keywords

image resolution; medical image processing; positron emission tomography; Siemens Hi-Rez PET scanner; TOF PET; Time-of-flight positron emission tomography; object radial dimension; random coincidence; random reduction; randoms effect; signal-to-noise-ratio; spatial uncertainty; time resolution; Detectors; Image resolution; Lanthanum; National electric code; Noise reduction; Positron emission tomography; Signal resolution; Signal to noise ratio; Spatial resolution; Time measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium Conference Record, 2005 IEEE

ISSN

1095-7863

Print_ISBN

0-7803-9221-3

Type

conf

DOI

10.1109/NSSMIC.2005.1596623

Filename

1596623