A breast molecular imaging hybrid pixel sensor test chip with low noise CMOS readout IC on fully depleted silicon-on-insulator design

Author

Nguyen, D. ; Cormican, H. ; Baysal, A. ; Wiswall, C. ; Kerr, T. ; Wang, J.M. ; Ma, D.

Author_Institution

Bioptics Inc., Tucson, AZ

fYear

2009

fDate

9-11 April 2009

Firstpage

1

Lastpage

4

Abstract

This paper reports the design of an innovative CMOS active pixel sensor (CAPS) using Silicon-on-Insulator (SOI) technology. The CAPS designs approach provides the flexibility and high density features of hybrid pixel sensors with photon integration architecture. This sensor is the key component for the optimized biomarker scanner. A proof-of-principle test chip, paying particular attention to the noise performance of the pixel, the conversion gain, front-end electronics (FEE) and readout speed, can be available for testing in 2009. The overall objective of this paper is to contribute to improved diagnosis, prognosis, and prediction of breast cancer disease through the development of a very high conversion gain, low noise Photon Integration CMOS Imager. The design target for fluorescent detection limit with the CAPS is 4.49 fluorophores / mum2.

Keywords

CMOS integrated circuits; biomedical optical imaging; cancer; patient diagnosis; readout electronics; silicon-on-insulator; CMOS active pixel sensor; breast cancer disease prediction; breast molecular imaging; conversion gain; front-end electronics; fully depleted silicon-on-insulator design; hybrid pixel sensor test chip; low noise CMOS readout IC; optimized biomarker scanner; patient diagnosis; photon integration architecture; prognosis; proof-of-principle test chip; readout speed; silicon-on-insulator technology; Breast; CMOS image sensors; CMOS integrated circuits; Electronic equipment testing; Hybrid integrated circuits; Integrated circuit noise; Integrated circuit testing; Molecular imaging; Pixel; Silicon on insulator technology;

fLanguage

English

Publisher

ieee

Conference_Titel

Complex Medical Engineering, 2009. CME. ICME International Conference on

Conference_Location

Tempe, AZ

Print_ISBN

978-1-4244-3315-5

Electronic_ISBN

978-1-4244-3316-2

Type

conf

DOI

10.1109/ICCME.2009.4906588

Filename

4906588