A multi-agent system to simulate an apoptosis model of B-CD5 cells

The aim of immune simulations is to reproduce in machina, in vitro and in vivo experimentation. It is then possible to test the cell models and the consequences of their interactions. Thus, by comparing the simulation results with the experimentation results the validity of the model can be demonstrated. A distributed and cooperative system can advantageously be modeled by a multiagent system. With this approach, the abstraction needed to model these phenomena is reduced. The immune system is included in highly cooperative and distributed systems. Moreover, it is quite easy to add or remove entities in the model and to improve their behaviors. In this paper, we present a multiagent system that reproduces in machina a set of in-vitro experimentation on the apoptosis phenomena