• DocumentCode
    3298632
  • Title

    Relationship between deformation and electrical impedance in Mouse skin

  • Author

    Nesbitt, R.S. ; Pandit, V.A. ; Karande, P. ; Kotha, S.P.

  • Author_Institution
    Rensselaer Polytech. Inst., Troy, NY, USA
  • fYear
    2011
  • fDate
    1-3 April 2011
  • Firstpage
    1
  • Lastpage
    2
  • Abstract
    Skin impedance is an excellent surrogate marker of skin permeability. Physical and chemical modalities that serve to increase skin permeability have direct applications in transdermal drug delivery. We have shown that the electrical impedance of skin, and consequently its permeability, can be changed by up to 60% by uniaxial stretching. This is of significant because electrical impedance has been directly correlated to skin´s permeability.
  • Keywords
    bioelectric phenomena; biomechanics; biomedical measurement; deformation; drug delivery systems; electric impedance measurement; permeability; skin; deformation; electrical impedance; mouse skin; skin permeability; transdermal drug delivery; uniaxial stretching; Impedance; Impedance measurement; Permeability; Probes; Skin; Strain; Voltage measurement;
  • fLanguage
    English
  • Publisher
    ieee
  • Conference_Titel
    Bioengineering Conference (NEBEC), 2011 IEEE 37th Annual Northeast
  • Conference_Location
    Troy, NY
  • ISSN
    2160-7001
  • Print_ISBN
    978-1-61284-827-3
  • Type

    conf

  • DOI
    10.1109/NEBC.2011.5778608
  • Filename
    5778608
    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=49&DC=3298632