Title :
Low-noise wide dynamic range readout circuit for multi-stage microfluidic cell sorting systems
Author :
Geheb, Benjamin R. ; Grafton, Meggie M G ; Jang, JaeHyuk ; Reece, Lisa M. ; Leary, James F. ; Kwon, Jong-Kee ; Jung, Byunghoo
Author_Institution :
Dept. of Electr. & Comput. Eng., Purdue Univ., West Lafayette, IN
Abstract :
The proposed sensor interface minimizes the optical detection system size while maximizing its overall efficiency (both power and sensitivity) of a multi-stage microfluidic cell sorter system. The proposed SigmaDelta sensor interface achieves at least one order of magnitude higher sensitivity while consuming less power (2mW) as compared to the traditional operational amplifier based transimpedance amplifier sensor interface. The proposed SigmaDelta sensor interface will be used to complete a full implementation of the developed multi-stage microfluidic system that would prove to be a great advancement in microfluidic cell sorting technology.
Keywords :
bioMEMS; biological techniques; cellular biophysics; microfluidics; optical sensors; low-noise readout circuit; microfluidic cell sorting systems; multistage sorting systems; optical detection; power 2 mW; sensor interface; transimpedance amplifier; wide dynamic range readout circuit; Circuits; Dynamic range; High power amplifiers; Microfluidics; Operational amplifiers; Optical amplifiers; Optical sensors; Sensor systems; Sorting; Stimulated emission;
Conference_Titel :
Life Science Systems and Applications Workshop, 2009. LiSSA 2009. IEEE/NIH
Conference_Location :
Bethesda, MD
Print_ISBN :
978-1-4244-4292-8
Electronic_ISBN :
978-1-4244-4293-5
DOI :
10.1109/LISSA.2009.4906704
