Title :
Enzymatic glucose sensor based on electrospun Mn2O3-Ag nanofibers
Author :
Huang, Shan ; Ding, Yu ; Lei, Yu
Author_Institution :
Univ. of Connecticut, Storrs, CT, USA
Abstract :
The Mn2O3-Ag nanofibers were fabricated by electrospinning PVP sol-gel solution containing Mn(NO3)2 and AgNO3, followed by calcination in air at 500 °C for 3 h. The as-prepared Mn2O3-Ag nanofibers were employed as the immobilization matrix for glucose oxidase (GOD) to construct an amperometric sensor for glucose detection in pH 7 phosphate buffer. The Mn2O3-Ag-GOD modified electrode demonstrated fast response to glucose, along with high sensitivity and excellent selectivity. Based on these good results, the Mn2O3-Ag based composites were proved to be a promising biosensing platform for the construction of glucose biosensor.
Keywords :
amperometric sensors; biochemistry; biomedical electrodes; biosensors; calcination; electrospinning; enzymes; manganese compounds; molecular biophysics; nanocomposites; nanofibres; nanomedicine; nanosensors; pH; silver; Mn2O3-Ag; PVP sol-gel solution; amperometric sensor; biosensor; calcination; electrode; electrospinning; electrospun; enzymatic glucose sensor; glucose oxidase; nanofibers; pH; Biosensors; Electric potential; Electrodes; Nanoparticles; Sensitivity; Sugar;
Conference_Titel :
Bioengineering Conference (NEBEC), 2011 IEEE 37th Annual Northeast
Conference_Location :
Troy, NY
Print_ISBN :
978-1-61284-827-3
DOI :
10.1109/NEBC.2011.5778661