Modeling and simulation of novel method of single cell viability detection via electrical measurement using dual nanoprobes

Previously, a novel method for cell viability detection using dual nanoprobe was demonstrated. By using finite element approach, four more factors, i.e. material types, cross-sectional shapes, opening gaps and penetration depth of the dual, have been studied in the present paper. In brief, the dual nanoprobes work by slightly penetrating the cell wall and measure the current that flow in the cells when exposed to a voltage. The main advantage of this method is that it does not consume any chemicals, it produces instantaneous and quantitative results, and tested cells are able to heal themselves and can be subjected for further testing due to the small diameter of the nanoprobes.