Title :
A novel method for recording wall strain in a murine vein graft model
Author :
Favreau, John T. ; Yu, Peng ; Ozaki, C. Keith ; Gaudette, Glenn R.
Author_Institution :
Dept. of Biomed. Eng., Worcester Polytech. Inst., Worcester, MA, USA
Abstract :
The failure of venous grafts that are placed in the arterial circulation is a significant clinical problem that should be addressed by researchers. One factor that is believed to play a role in causing these failures is changes in the wall strain environment. In this study we present a novel approach to recording wall strain in a murine model and demonstrate our ability to differentiate strains between arteries and veins. Extending to human conditions in the near future, this method can be utilized to elucidate the role of vessel wall strains in vein graft failure.
Keywords :
blood vessels; haemodynamics; prosthetics; arterial circulation; murine vein graft model; venous graft failure; wall strain; Arteries; Mice; Strain; Surgery; Tensile stress; Veins;
Conference_Titel :
Bioengineering Conference (NEBEC), 2011 IEEE 37th Annual Northeast
Conference_Location :
Troy, NY
Print_ISBN :
978-1-61284-827-3
DOI :
10.1109/NEBC.2011.5778707