Title :
Rheometry of irregularly shaped anisotropic biological samples
Author :
Cirka, H.A. ; Farr, W.W. ; Koehler, S.A. ; Billiar, K.L.
Author_Institution :
Worcester Polytech. Inst., Worcester, MA, USA
Abstract :
Quantification of viscoelastic properties of soft fibrous protein gels and tissue biopsies is vital to the study of disease progression and wound healing, among other research areas. The aim of this work is to establish a method of testing irregularly-shaped and anisotropic biological samples. This method has been tested with samples that have G´ in the range of 10-500 Pa and sizes of approximately 15 mm in diameter. Future aims of this work include characterizing clots from acute stroke patients and studying anisotropic shear in fibrous biopolymer gels.
Keywords :
biological tissues; biomechanics; biomedical materials; cellular biophysics; diseases; polymer gels; proteins; viscoelasticity; acute stroke patients; anisotropic shear; disease progression; fibrous biopolymer gels; irregularly shaped anisotropic biological samples; rheometry; soft fibrous protein gels; tissue biopsies; viscoelastic properties; wound healing; Anisotropic magnetoresistance; Geometry; Proteins; Shape; Testing; Torque;
Conference_Titel :
Bioengineering Conference (NEBEC), 2011 IEEE 37th Annual Northeast
Conference_Location :
Troy, NY
Print_ISBN :
978-1-61284-827-3
DOI :
10.1109/NEBC.2011.5778710
