Title :
Cancer Tumor Detection by Gene Expression Data Exploration Using a Genetic Fuzzy System
Author :
Shabgahi, Abbas Zibakhsh ; Abadeh, Mohammad Saniee
Author_Institution :
Fac. of Electr. & Comput. Eng., Tarbiat Modares Univ., Tehran, Iran
Abstract :
Classification of different tumors in cancer detection and drug identification is very important task. Prior cancer classification was based on clinical information that has a limited ability for detection and debugging. Recently, micro array technology has enabled monitoring the description of thousands of genes simultaneously. Rule-based expert systems are often used for decision support in various fields such as error detection, biology and medicine. In some fields like medicine it is preferred to use classifiers that are not in form of black box (like neural network) because it helps users to understand the knowledge of classifier. Fuzzy rule based classifiers are suitable for this matter because they are simply interpretable and they haven´t deterministic classifiers limitation. In this paper, we proposed cancer detection on Global Cancer Map dataset by creating fuzzy rule with genetic algorithm. We´ll show that our approach is useful in cancer tumor detection based on the results.
Keywords :
cancer; data handling; decision support systems; expert systems; fuzzy set theory; genetic algorithms; medical information systems; pattern classification; tumours; black box; cancer classification; cancer tumor detection; decision support; drug identification; fuzzy rule; fuzzy rule based classifiers; gene expression data exploration; genetic algorithm; genetic fuzzy system; global cancer map dataset; medicine; microarray technology; rule based expert systems; tumor classification; Cancer Classification; Fuzzy Rule Learning; Gene Expression Data; Genetic Algorithm;
Conference_Titel :
Developments in E-systems Engineering (DeSE), 2011
Conference_Location :
Dubai
Print_ISBN :
978-1-4577-2186-1
DOI :
10.1109/DeSE.2011.46