Modeling and simulation of the ultrasound signal backscattered by blood

Author

Fontaine, Isabelle ; Cloutier, Guy

Author_Institution

Lab. of Biomed. Eng., Clinical Res. Inst. of Montreal, Que., UK

Volume

2

fYear

1999

fDate

36434

Abstract

A new model is proposed to simulate the power backscattered by blood. The model is that of a space-invariant linear system which takes into consideration the blood stochastic scattering properties as well as the characteristics of the ultrasound system. The model allowed the study of the backscattered power as a function of the hematocrit for nonaggregating red blood cells (RBCs), and the level of RBC aggregation determined by the flow shear rate. RBC aggregation was simulated in a Couette flow at 40% hematocrit and shear rates of 0.01 s^-1 to 10 s^-1. For nonaggregating RBCs, the power as a function of the hematocrit matched theoretical predictions and experimental results. The maximum aggregation and backscattered power were obtained around 0.6 s^-1

Keywords

Couette flow; aggregation; backscatter; bioacoustics; biomedical ultrasonics; blood; cellular biophysics; haemorheology; physiological models; shear flow; ultrasonic scattering; Couette flow; RBC aggregation; backscattered power; backscattered ultrasound signal; blood; blood stochastic scattering properties; flow shear rate; hematocrit; modeling; nonaggregating red blood cells; shear rates; simulation; space-invariant linear system; ultrasound system; Acoustic scattering; Aggregates; Blood; Frequency; Laboratories; Particle scattering; Plasma properties; Power system modeling; Solid modeling; Ultrasonic imaging;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.804199

Filename

804199