Title :
A method to determine the chemokinetic effect of growth factors using the Fischer equation
Author :
Baskaran, H. ; Hamoen, K. ; Pemmpanani, A.J. ; Morgan, J. ; Berthiaume, F.
Author_Institution :
Center for Eng. in Med., Harvard Med. Sch., Boston, MA, USA
Abstract :
We describe a simple method that can be used to determine the chemokinetic coefficient of cells at the boundary of an advancing cell monolayer. The method is based on the use of the Fischer equation and requires only simple measurements of cell proliferation and cell migration. Several samples can be simultaneously studied with reliable and reproducible results using this method
Keywords :
biological techniques; cell motility; molecular biophysics; Fischer equation; advancing cell monolayer; boundary; cell migration; cell motility; cell proliferation; chemokinetic coefficient; chemokinetic effect; growth factors; Biomedical engineering; Cells (biology); Epidermis; Equations; Hospitals; Humans; Microscopy; Optical propagation; Pediatrics; Wounds;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.804343
