Title :
Modeling the growth of three-dimensional tissues
Author :
Belgacem, B.Y. ; Zygourakis, K. ; Markenscoff, P.
Author_Institution :
Dept. of Electr. & Comput. Eng., Houston Univ., TX, USA
Abstract :
We report the development of a model that describes the dynamic behavior of a population of cells that migrate and proliferate to fill a three-dimensional scaffold. This model is then applied to study how cell migration and the density or spatial distribution of seed cells affect the tissue growth rates
Keywords :
biological tissues; cell motility; physiological models; cell migration; density; dynamic behavior; modeling; population; seed cells; spatial distribution; three-dimensional scaffold; three-dimensional tissues; tissue growth rates; Biological materials; Biomedical engineering; Chemical engineering; Computational modeling; Degradation; Extracellular; Polymers; Protein engineering; Shape; Wounds;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.804346
