Parallel-coordinates visualization of capillary transport model analysis

In model analysis the behavior, sensitivity, and identifiability of a physiological model are examined in order to assess the suitability of the model for use in parameter identification. Model analysis can become a daunting task when large numbers of parameter combinations are possible within a single model We applied a parallel-coordinates multidimensional visualization method to the analysis of the 2-region Sangren-Sheppard model of pulmonary capillary exchange. We assessed the usefulness of this method in efficiently examining the behavior, sensitivity, and indentifiability of the model at many combinations of extravascular volume, permeability-surface area product, and flow