Three-dimensional models of regionally ischemic left ventricle

Author

Mazhari, Reza ; McCulloch, Andrew D.

Author_Institution

Dept. of Bioeng., California Univ., San Diego, La Jolla, CA, USA

Volume

2

fYear

1999

fDate

36434

Abstract

Regional wall mechanics were analyzed in a finite element model of the canine left ventricle that included measured three-dimensional geometry and myofiber angles, nonlinear anisotropic material properties, calcium-activated systolic myofilament tension development, and the newly reported observation of significant active stress transverse to the myofiber axis. Strain distributions in the model agreed well with experimental measurements in anesthetized dogs during left anterior descending (LAD) coronary artery occlusion

Keywords

biomechanics; biomembrane transport; blood vessels; cardiovascular system; finite element analysis; muscle; physiological models; Ca; LAD coronary artery occlusion; active stress; anesthetized dogs; calcium-activated systolic myofilament tension development; canine left ventricle; finite element model; left anterior descending coronary artery occlusion; myofiber angles; myofiber axis; nonlinear anisotropic material properties; regional wall mechanics; regionally ischemic left ventricle; strain distributions; three-dimensional geometry; three-dimensional models; Anisotropic magnetoresistance; Arterial occlusion; Dogs; Finite element methods; Geometry; Mechanical factors; Mechanical variables measurement; Solid modeling; Strain measurement; Stress measurement;

fLanguage

English

Publisher

ieee

Conference_Titel

[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint

Conference_Location

Atlanta, GA

ISSN

1094-687X

Print_ISBN

0-7803-5674-8

Type

conf

DOI

10.1109/IEMBS.1999.804367

Filename

804367