DocumentCode
3312370
Title
Meta-analysis and Network Analysis of Five Ovarian Cancer Gene Expression Dataset
Author
Dong, Hua ; Hong, Shengjun ; Xu, Xiaomin ; Xiao, Yanghua ; Jin, Li ; Xiong, Momiao
Author_Institution
State Key Lab. of Genetic Eng., Fudan Univ., Shanghai, China
Volume
1
fYear
2010
fDate
28-31 May 2010
Firstpage
242
Lastpage
246
Abstract
Ovarian cancer is the fifth leading cause of death from cancer in women and the leading cause of death from gynecological cancer. Here we present a meta-analysis of five gene expression data sets of 432 ovarian cancer and 42 adjacent normal samples in total. We indentified 3 genes: NDN, RNASE4, IGFBP4 were significantly differentially expressed in both five data sets. After combined the dataset by meta-analysis, 3722 genes were significant (p-value
Keywords
Biological information theory; Biomedical computing; Cancer; Computer networks; Computer science; Gene expression; Genetic engineering; Laboratories; Neoplasms; Proteins; co-expression network; meta-analysis; microarray; ovarian cancer;
fLanguage
English
Publisher
ieee
Conference_Titel
Computational Science and Optimization (CSO), 2010 Third International Joint Conference on
Conference_Location
Huangshan, Anhui, China
Print_ISBN
978-1-4244-6812-6
Electronic_ISBN
978-1-4244-6813-3
Type
conf
DOI
10.1109/CSO.2010.245
Filename
5533001
Link To Document