Title :
Lung injury biomechanics: an in vitro model and clinical implications
Author_Institution :
Dept. of Bioeng., Pennsylvania Univ., Philadelphia, PA, USA
Abstract :
These experimental findings using a cell culture model for ventilator-induced lung injury confirm the hypothesis that cellular deformations corresponding to high lung volumes result in alveolar epithelial injury, and yield important insight into injury mechanisms and preventive measures
Keywords :
biomechanics; cellular biophysics; diseases; lung; physiological models; alveolar epithelial injury; cell culture model; cellular deformations; clinical implications; in vitro model; injury mechanisms; lung injury biomechanics; lung volumes; preventive measures; ventilator-induced lung injury; Biomechanics; Blood; Capacitive sensors; Deformable models; Fluorescence; In vitro; Injuries; Lungs; Permeability; Ventilation;
Conference_Titel :
[Engineering in Medicine and Biology, 1999. 21st Annual Conference and the 1999 Annual Fall Meetring of the Biomedical Engineering Society] BMES/EMBS Conference, 1999. Proceedings of the First Joint
Conference_Location :
Atlanta, GA
Print_ISBN :
0-7803-5674-8
DOI :
10.1109/IEMBS.1999.804493
