Title :
Notice of Retraction
Research Progress on Polysaccharides Hypoglycemic Mechanism and Therapeutic Potential
Author :
Fei Wang ; Li-Ping Wei ; Zhong Zhang ; Tao Feng
Author_Institution :
Coll. of Chem. & Life Sci., Guangdong Univ. of Petrochem. Technol., Maoming, China
Abstract :
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Plenty of experiments have demonstrated that polysaccharides have effect of hyperglycemic. We review the possible mechanisms that polysaccharide reduce blood sugar and the therapeutic potential in this paper. The mechanisms include improve islet morphology and function, stimulate insulin secretion, enhance the insulin sensitivity, improve glycometabolism, modulate autoimmunity, improve the activities of glycometabolism related enzymes, suppress insulin metabolism, ameliorate the lipid metabolism and inhibit alpha-glucosidase. Polysaccharides not only reduce the blood sugar but also improvement the complications of diabetes mellitus such as dyslipidemia, diabetic nephropathy et al. Suggest polysaccharides possess the possibility of being developed from a new anti-diabetic agent.
Keywords :
biochemistry; blood; diseases; drugs; enzymes; kidney; macromolecules; molecular biophysics; patient treatment; reviews; alpha-glucosidase inhibition; antidiabetic agent; autoimmunity modulation; blood sugar reduction; diabetes mellitus; diabetic nephropathy; dyslipidemia; enzymes; glycometabolism; insulin metabolism suppression; insulin secretion; insulin sensitivity enhancement; islet function; islet morphology; lipid metabolism amelioration; polysaccharides hypoglycemic mechanism; review; therapeutic potential; Biochemistry; Diabetes; Immune system; Insulin; Mice; Rats; Sugar;
Conference_Titel :
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-5088-6
DOI :
10.1109/icbbe.2011.5780159