DocumentCode
3322060
Title
Notice of Retraction
The Sprayable Agarose/Gelatin as Wound Skin Dressing
Author
Peng Chen ; Cui Lou ; Lingmin Zhang ; Bin Chu ; Lei Bao ; Shunqing Tang
Author_Institution
Biomed. Eng. Inst., Jinan Univ., Guangzhou, China
fYear
2011
fDate
10-12 May 2011
Firstpage
1
Lastpage
3
Abstract
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Rapid and exact healing of skin wound, such as severe burns, trauma, diabetic, decubitus or venous stasis ulcers, is desirable in clinical. In this paper, the degraded agarose was mixed with gelatin as sprayable wound skin dressing. Agarose with different molecular weight was obtained through the degradation of agarose with hydrogen peroxide for different intervals. The formation of agarose gel was monitored by scattered light turbidimeter. The degraded agarose was activated by epichlorohydrin. The activated agarose/gelatin solution was sprayed to form gel coating rabbit wound skin. The gel dressing was not toxic and had a good repair effect on rabbit skin lesion without infection and liquid exudation. H&E staining results showed that the repair tissue was similar to the normal one. The activated low molecular agarose /gelatin gels are promising biomaterials as wound dressings for healing burns or ulcers.
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Rapid and exact healing of skin wound, such as severe burns, trauma, diabetic, decubitus or venous stasis ulcers, is desirable in clinical. In this paper, the degraded agarose was mixed with gelatin as sprayable wound skin dressing. Agarose with different molecular weight was obtained through the degradation of agarose with hydrogen peroxide for different intervals. The formation of agarose gel was monitored by scattered light turbidimeter. The degraded agarose was activated by epichlorohydrin. The activated agarose/gelatin solution was sprayed to form gel coating rabbit wound skin. The gel dressing was not toxic and had a good repair effect on rabbit skin lesion without infection and liquid exudation. H&E staining results showed that the repair tissue was similar to the normal one. The activated low molecular agarose /gelatin gels are promising biomaterials as wound dressings for healing burns or ulcers.
Keywords
biological tissues; biomedical materials; cellular biophysics; gelatin; gels; hydrogen compounds; injuries; light scattering; molecular weight; skin; wounds; H2O2; agarose-gelatin solution; biomaterials; decubitus; diabetic; epichlorohydrin; gel coating rabbit wound skin; hydrogen peroxide; liquid exudation; low molecular agarose-gelatin gels; molecular weight; scattered light turbidimeter; skin wound healing; sprayable wound skin dressing; trauma; venous stasis ulcers; Degradation; Maintenance engineering; Mice; Polymers; Rabbits; Skin; Wounds;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location
Wuhan
ISSN
2151-7614
Print_ISBN
978-1-4244-5088-6
Type
conf
DOI
10.1109/icbbe.2011.5780276
Filename
5780276
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