Title :
A repulsive clustering algorithm for gene expression data
Author :
Cheng, Chyun-Shin ; Wang, Shiuan-Sz
Author_Institution :
Dept. of Electron. Eng., Tung Nan Inst. of Technol., Taipei, Taiwan
Abstract :
Facing the development of microarray technology, clustering is currently a leading technique to gene expression data analysis. In this paper we propose a novel algorithm called repulsive clustering, which is developed for the use of gene expression data analysis. Our performance demonstration on several synthetic and real gene expression data sets show that the repulsive clustering algorithm, compared with some other well-known clustering algorithms, is capable of not only producing even higher quality output, but also easier to implement for immediate use on various situations.
Keywords :
arrays; biological techniques; data analysis; genetics; biophysical techniques; gene expression data analysis; higher quality output; human cancer cells line data sets; performance demonstration; repulsive clustering algorithm; synthetic gene expression data sets; synthetic random data set; yeast cell cycle data; Algorithm design and analysis; Clustering algorithms; Data analysis; Data engineering; Diseases; Gene expression; Magnetic analysis; Performance analysis; Switches; Tree data structures;
Conference_Titel :
Bioinformatics and Bioengineering, 2003. Proceedings. Third IEEE Symposium on
Print_ISBN :
0-7695-1907-5
DOI :
10.1109/BIBE.2003.1188980