Title :
Ultrasound-guided injections into the mouse embryonic brain
Author :
Turnbull, Daniel H. ; Olsson, Martin ; Fishell, Gordon ; Joyner, Alexandra L.
Author_Institution :
Inst. of Biomolecular Med., New York Univ. Med. Center, NY, USA
Abstract :
The authors have modified a 40-50 MHz ultrasound imaging system to allow image-guided injections into targeted brain regions of living mouse embryos. The injection technique is described, and example injections are shown. The significance of this research in basic biological science and the potential impact on future attempts at in utero therapy are described
Keywords :
bioacoustics; biological techniques; brain; ultrasonic imaging; 40 to 50 MHz; 40-50 MHz ultrasound imaging system; basic biological science; biological research technique; image-guided injections; in utero therapy; mouse embryonic brain; targeted brain regions; ultrasound-guided injections; Abdomen; Biomembranes; Embryo; Mice; Needles; Pregnancy; Probes; Rubber; Suspensions; Ultrasonic imaging;
Conference_Titel :
Ultrasonics Symposium, 1997. Proceedings., 1997 IEEE
Conference_Location :
Toronto, Ont.
Print_ISBN :
0-7803-4153-8
DOI :
10.1109/ULTSYM.1997.661857