Notice of RetractionStudy on the Extraction and Clathration Processes of Volatile Oils in Wulian Antidiarrheic Granules

Notice of Retraction

After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.

We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.

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Volatile oil contained in Atractylodes macrocephala, Zingiberis rhizoma, Costustroot and Radix glycyrrhizae, which were components in Wulian antidiarrheic granules, was extracted by distillation, the optimum extraction condition was determined by observing the imbitition amount, soaking time, extracting time and crashing degree, based on the dissolution ratio of volatile oil. Volatile oil was wrapped up with β-cyclodextrin (β-CD) to stabilize the preparation and ensure the therapeutic effect, the optimum clathration condition was investigated with orthogonal design by determining the yield rate of clathratio and availability of volatile oil. The results showed that the best extraction process of volatile oils was as following: Atractylodes macrocephala, Zingiberis rhizoma, Costustroot and Radix et rhizome glycyrrhizae were crushed into coarse powder, no soak, extracted 6 hours with 8 times amount of water; the clathration technology of volatile oil was: proportion of β-CD and volatile oil was 4:1, β-CD and water was 1:8, clathratio for 30 min at 40°C.