New attenuation correction for the HRRT using transmission scatter correction and total variation regularization

In the standard software for the Siemens HRRT PET scanner the most commonly used segmentation in the ¿-map reconstruction for human brain scans is MAP-TR. Problems with bias in the lower cerebellum and pons in HRRT brain images have been reported. The main source of the problem is poor bone / soft tissue segmentation in these regions and the lack of scatter correction in the ¿-map reconstruction. In this paper we describe and validate the new TXTV segmentation method (included in the HRRTU 1.0 and 1.1 user software) aimed at solving the bias problem.