Title :
Video image based attenuation correction for PETbox, a preclinical PET tomograph
Author :
Taschereau, Richard ; Bao, Qinan ; Rannou, Fernando R. ; Chatziioannou, Arion F.
Author_Institution :
Dept. of Mol. & Med. Pharmacology, Univ. of California Los Angeles, Los Angeles, CA, USA
fDate :
Oct. 24 2009-Nov. 1 2009
Abstract :
PETBox is a new simplified bench top PET scanner dedicated for pre-clinical imaging of mice. It has only two facing detector heads in a static gantry. Using iterative methods, limited-angle reconstruction of 3D images is possible. The geometry of the PETBox is such that very oblique emission angles are detected traversing significant lengths of tissue, making attenuation correction necessary. To that effect, we have developed a method by which two orthogonal optical views are combined to create a 3-dimensional estimate of the subject. This estimate is used to produce attenuation correction data that significantly improve the quantitative accuracy of the reconstructed images. In this paper, we present the method and evaluate its accuracy.
Keywords :
biological tissues; image reconstruction; iterative methods; medical image processing; positron emission tomography; PET scanner; PETBox; Positron Emission Tomography; iterative methods; limited-angle image reconstruction; oblique emission angles; orthogonal optical views; preclinical imaging; static gantry; video image based attenuation correction; Attenuation; Detectors; Geometrical optics; Head; Image reconstruction; Iterative methods; Mice; Optical attenuators; Optical imaging; Positron emission tomography;
Conference_Titel :
Nuclear Science Symposium Conference Record (NSS/MIC), 2009 IEEE
Conference_Location :
Orlando, FL
Print_ISBN :
978-1-4244-3961-4
Electronic_ISBN :
1095-7863
DOI :
10.1109/NSSMIC.2009.5401754
