DocumentCode
3329107
Title
Functional polypyrrole coatings for wirelessly controlled magnetic microrobots
Author
Sivaraman, Kartik M. ; Chatzipirpiridis, George ; Becsek, B. ; Luhmann, T. ; Ergeneman, Olgac ; Nelson, Bradley J. ; Pane, Salvador
Author_Institution
Inst. of Robot. & Intell. Syst. (IRIS), ETH Zurich, Zurich, Switzerland
fYear
2013
fDate
16-18 Jan. 2013
Firstpage
22
Lastpage
25
Abstract
A wirelessly controlled magnetic microrobot has been proposed to diagnose and treat pathologies in the posterior segment of the human eye. The robot consists of a magnetic CoNi platform with a conformal coating of functional polymers. Electrodeposition has been the preferred method to fabricate and to functionalize the microrobot. Poly(pyrrole), a widely studied intrinsically conductive polymer has been investigated as a biocompatible coating to reduce biofouling, and as a coating that can release incorporated drugs on demand. The mechanism of redox cycling has been investigated to reduce the stiction of NIH 3T3 fibroblasts onto poly(pyrrole) surfaces. To demonstrate triggered drug release, Rhodamine B has been incorporated into the Ppy matrix as a model drug. Rapid Rhodamine B release is obtained when eddy current losses are induced by alternating magnetic fields on the CoNi substrates underneath these films.
Keywords
biomagnetism; biomedical equipment; cellular biophysics; conducting polymers; diseases; drug delivery systems; drugs; eddy current losses; electrodeposition; eye; magnetic materials; microrobots; oxidation; patient diagnosis; polymer films; reduction (chemical); vision; CoNi; NIH fibroblast stiction; Ppy matrix; alternating magnetic fields; biocompatible coating; biofouling; conformal coating; drug release; eddy current losses; electrodeposition; functional polymers; functional polypyrrole coatings; human eye; intrinsically conductive polymer; magnetic platform; pathologies; patient diagnosis; patient treatment; poly(pyrrole) surfaces; posterior segment; rapid rhodamine B release; redox cycling; wirelessly controlled magnetic microrobots; Cells (biology); Coatings; Fibroblasts; Magnetic fields; Plastics; Substrates; Surface treatment;
fLanguage
English
Publisher
ieee
Conference_Titel
Point-of-Care Healthcare Technologies (PHT), 2013 IEEE
Conference_Location
Bangalore
Print_ISBN
978-1-4673-2765-7
Electronic_ISBN
978-1-4673-2766-4
Type
conf
DOI
10.1109/PHT.2013.6461275
Filename
6461275
Link To Document