DocumentCode :
3329107
Title :
Functional polypyrrole coatings for wirelessly controlled magnetic microrobots
Author :
Sivaraman, Kartik M. ; Chatzipirpiridis, George ; Becsek, B. ; Luhmann, T. ; Ergeneman, Olgac ; Nelson, Bradley J. ; Pane, Salvador
Author_Institution :
Inst. of Robot. & Intell. Syst. (IRIS), ETH Zurich, Zurich, Switzerland
fYear :
2013
fDate :
16-18 Jan. 2013
Firstpage :
22
Lastpage :
25
Abstract :
A wirelessly controlled magnetic microrobot has been proposed to diagnose and treat pathologies in the posterior segment of the human eye. The robot consists of a magnetic CoNi platform with a conformal coating of functional polymers. Electrodeposition has been the preferred method to fabricate and to functionalize the microrobot. Poly(pyrrole), a widely studied intrinsically conductive polymer has been investigated as a biocompatible coating to reduce biofouling, and as a coating that can release incorporated drugs on demand. The mechanism of redox cycling has been investigated to reduce the stiction of NIH 3T3 fibroblasts onto poly(pyrrole) surfaces. To demonstrate triggered drug release, Rhodamine B has been incorporated into the Ppy matrix as a model drug. Rapid Rhodamine B release is obtained when eddy current losses are induced by alternating magnetic fields on the CoNi substrates underneath these films.
Keywords :
biomagnetism; biomedical equipment; cellular biophysics; conducting polymers; diseases; drug delivery systems; drugs; eddy current losses; electrodeposition; eye; magnetic materials; microrobots; oxidation; patient diagnosis; polymer films; reduction (chemical); vision; CoNi; NIH fibroblast stiction; Ppy matrix; alternating magnetic fields; biocompatible coating; biofouling; conformal coating; drug release; eddy current losses; electrodeposition; functional polymers; functional polypyrrole coatings; human eye; intrinsically conductive polymer; magnetic platform; pathologies; patient diagnosis; patient treatment; poly(pyrrole) surfaces; posterior segment; rapid rhodamine B release; redox cycling; wirelessly controlled magnetic microrobots; Cells (biology); Coatings; Fibroblasts; Magnetic fields; Plastics; Substrates; Surface treatment;
fLanguage :
English
Publisher :
ieee
Conference_Titel :
Point-of-Care Healthcare Technologies (PHT), 2013 IEEE
Conference_Location :
Bangalore
Print_ISBN :
978-1-4673-2765-7
Electronic_ISBN :
978-1-4673-2766-4
Type :
conf
DOI :
10.1109/PHT.2013.6461275
Filename :
6461275
Link To Document :
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