Range and density variations monitoring during proton therapy based on time-of-flight detection of prompt gamma radiation

Author

Biegun, Aleksandra K. ; Seravalli, Enrica ; Lopes, Patricia Cambraia ; Rinaldi, Ilaria ; Pinto, Marco ; Oxley, David C. ; Dendooven, Peter ; Verhaegen, Frank ; Parodi, Katia ; Schaart, Dennis R. ; Crespo, Paulo

Author_Institution

Delft Univ. of Technol., Delft, Netherlands

fYear

2011

fDate

23-29 Oct. 2011

Firstpage

3492

Lastpage

3495

Abstract

The aim of this work is to seek for an optimal angular detection of prompt photons emitted perpendicularly to the beam direction using a time-of-flight technique, which enables a huge neutron background rejection. A homogeneous PMMA phantom was studied. The prompt photon profile correlates well with the dose distal fall-off when the proper selection of θ=90°±0.7° of the emitted prompt gamma rays is made. The correlation to the dose can be detected with the present method with an accuracy of up to 4 mm at 50% height of the prompt gamma rays profile.

Keywords

biological effects of gamma-rays; dosimetry; phantoms; radiation therapy; time of flight spectra; density variation monitoring; dose correlation; homogeneous PMMA phantom; huge neutron background rejection; prompt gamma radiation; proton therapy; time-of-flight detection; Detectors; Particle beams;

fLanguage

English

Publisher

ieee

Conference_Titel

Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC), 2011 IEEE

Conference_Location

Valencia

ISSN

1082-3654

Print_ISBN

978-1-4673-0118-3

Type

conf

DOI

10.1109/NSSMIC.2011.6152641

Filename

6152641