DocumentCode
3330282
Title
Notice of Retraction
Protective Effect of Essential Oil from Zingiber Officinale (Zingiberaceae) on Acute Alcohol-Induced Liver Injury in Mice
Author
Ping Liu ; Jingming Li ; Liyan Ma ; Shuyan Li ; Yuanying Ni
Author_Institution
Coll. of Food Sci. & Nutritional Eng., China Agric. Univ., Beijing, China
fYear
2011
fDate
10-12 May 2011
Firstpage
1
Lastpage
4
Abstract
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Oxidative stress and lipid abnormalities after ethanol consumption are suggested to play a key role in the development of alcoholic liver injury. We investigated the induction of oxidative damage in association with triglyceride abnormalities in hepatic concentrations mice challenged with ethanol administration. Also the protective effect of ginger essential oil (GEO) extracted with supercritical carbon dioxide against ethanol-induced liver injury was determined. Hepatic malondialdehyde, triglyceride level and the fat vacuoles score were increased significantly by ethanol administration. Ethanol administration decreased hepatic glutathione reduced level. GEO supplied through gavage for 30 days attenuated the induction of alcoholic liver injury. This study demonstrated that GEO extract with supercritical carbon dioxide caused a decrease in lipid peroxidation, an increase of plasma antioxidant capacity and a reduction in hepatic injury.
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Oxidative stress and lipid abnormalities after ethanol consumption are suggested to play a key role in the development of alcoholic liver injury. We investigated the induction of oxidative damage in association with triglyceride abnormalities in hepatic concentrations mice challenged with ethanol administration. Also the protective effect of ginger essential oil (GEO) extracted with supercritical carbon dioxide against ethanol-induced liver injury was determined. Hepatic malondialdehyde, triglyceride level and the fat vacuoles score were increased significantly by ethanol administration. Ethanol administration decreased hepatic glutathione reduced level. GEO supplied through gavage for 30 days attenuated the induction of alcoholic liver injury. This study demonstrated that GEO extract with supercritical carbon dioxide caused a decrease in lipid peroxidation, an increase of plasma antioxidant capacity and a reduction in hepatic injury.
Keywords
carbon compounds; essential oils; injuries; liver; acute alcohol-induced liver injury; ethanol administration; ethanol consumption; ginger essential oil; hepatic concentrations; hepatic glutathione reduced level; hepatic injury; lipid abnormalities; lipid peroxidation; mice; oxidative damage; oxidative stress; plasma antioxidant capacity; protective effect; supercritical carbon dioxide; triglyceride abnormalities; zingiber officinale; Chemicals; Ethanol; Injuries; Lipidomics; Liver; Mice;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location
Wuhan
ISSN
2151-7614
Print_ISBN
978-1-4244-5088-6
Type
conf
DOI
10.1109/icbbe.2011.5780701
Filename
5780701
Link To Document