Cardiac MPI of mice over the complete heart cycle

Magnetic Particle Imaging (MPI) allows rapid imaging of magnetic tracer distributions with high sensitivity. We show volumetric in vivo heart images of a mouse. The concentration of the commercially available MR contrast agent was in a range which is approved for humans. Images at various stages of the cardiac cycle were reconstructed proving the unprecedented temporal resolution of MPI. The results suggest that MPI can be scaled up to human sized scanners enabling, e.g., dynamic imaging of coronary blood flow.