Title :
Development of the multiple sample injector using stepwise flow to prevent sample dilution
Author :
Kanai, Masaki ; Ikeda, Shingo ; Tanaka, Junichi ; Go, Jeung Sang ; Nakanishi, Hiroaki ; Shoji, Shuichi
Author_Institution :
Dept. of Electron., Inf. & Commun. Eng., Waseda Univ., Tokyo, Japan
Abstract :
This paper presents a concentration-conservative multiple sample injector. The stepwise flow was used to reduce dilution of the sample reagent while the reagent was injected into the sample collection outlet. By using CFD simulation, the concentration profile of the sample reagent was estimated. It was clearly shown that the concentration was kept in a sample outlet. For experimental evaluation, a sample injector was fabricated and the sample injection using stepwise flow was observed by a fluorescent measuring system.
Keywords :
digital simulation; flow control; flow simulation; flow visualisation; microfluidics; sample holders; CFD simulation; concentration profile; concentration-conservative multiple sample injector; fluorescent measuring system; sample collection outlet; sample dilution; sample reagent; sheath flow sample injector; stepwise flow; Biochemical analysis; Computational fluid dynamics; Degradation; Fluid flow measurement; Fluorescence; Laboratories; Switches; Tiles; Virtual prototyping; Volume measurement;
Conference_Titel :
Micro Electro Mechanical Systems, 2003. MEMS-03 Kyoto. IEEE The Sixteenth Annual International Conference on
Print_ISBN :
0-7803-7744-3
DOI :
10.1109/MEMSYS.2003.1189718