Title :
A silicon-micromachined pin for contact droplet printing
Author :
Tsai, Jane Gin Fai ; Chen, Zugen ; Nelson, Stanley ; Kim, Chang-Jin
Author_Institution :
Biomed. Eng. Inter-Departmental Program, California Univ., Los Angeles, CA, USA
Abstract :
This paper reports the design and fabrication of a micromachined silicon pin that serves as a novel contact-printing tool. More specific application is in the DNA and protein microarray field for small and precise droplet printing onto a solid support. Our goal is to develop low cost, high performance silicon pins as simple replacement of the stainless-steel pins used in typical microarray robots. The test results show an average droplet size of 38 μm in diameter, compared with over 100 μm for the commercial pins, as well as more consistent droplet sizes.
Keywords :
DNA; biomolecular electronics; drops; elemental semiconductors; micromachining; printing; proteins; silicon; surface tension; 100 micron; 38 micron; DNA microarray field; Si-micromachined pin; average droplet size; contact droplet printing; low cost high performance pins; microarray robots; precise droplet printing; protein microarray field; solid support; Costs; DNA; Fabrication; Pins; Printing; Proteins; Robots; Silicon; Solids; Testing;
Conference_Titel :
Micro Electro Mechanical Systems, 2003. MEMS-03 Kyoto. IEEE The Sixteenth Annual International Conference on
Print_ISBN :
0-7803-7744-3
DOI :
10.1109/MEMSYS.2003.1189744
