Title :
Automated DNA sequencing on gel images by digital techniques
Author :
Zhu, S.F. ; Zhang, Y.T.
Author_Institution :
Dept. of Biomed. Eng., Zhejiang Med. Univ., Hangzhou, China
fDate :
29 Oct-1 Nov 1998
Abstract :
DNA sequencing is one of the important aspects of genetic engineering. We applied digital image processing techniques to this study, and also introduced a recurring algorithm of adaptive segmentation to perform such sequencing. As shown in the experimental results, this method has its own characteristic. Specifically, it enhances the recognition of DNA sequence to become quicker and more efficient. Since the future of biotechnology is very promising, we believe that further research in this field using digital method is worthwhile
Keywords :
DNA; biochemistry; biological techniques; biology computing; biotechnology; electrophoresis; genetics; image segmentation; medical image processing; molecular configurations; Gaussian filtering; adaptive segmentation; automated DNA sequencing; digital image processing; gel images; genetic engineering; recurring algorithm; sequence recognition; single fragment reading; Amino acids; Biological information theory; Biomedical engineering; Biomedical optical imaging; DNA; Digital images; Genetic engineering; Optical distortion; Optical filters; Sequences;
Conference_Titel :
Engineering in Medicine and Biology Society, 1998. Proceedings of the 20th Annual International Conference of the IEEE
Conference_Location :
Hong Kong
Print_ISBN :
0-7803-5164-9
DOI :
10.1109/IEMBS.1998.745639
