Title :
An improved algorithm for the design of individually optimized dialysis profiles
Author :
Bachhiesl, P. ; Scharfetter, H. ; Kappel, F. ; Hutten, H.
Author_Institution :
Dept. of Biomed. Eng., Graz Univ. of Technol., Austria
fDate :
31 Oct-3 Nov 1996
Abstract :
An efficient algorithm for the optimization of process parameters during dialysis has been developed. It is possible to compute optimal concentrations of electrolytes in dialysis by solving a tracking problem for distinguished dynamic variables, which are indirectly influencing the status of the patient and can directly be modelled. The tracking problem was treated as a dynamic optimization problem, which has been solved by the application of a modified continuous descent procedure, which is known from the theory of unconstrained static minimization. The used method is characterized by its simple mode of application, short solution time and moderate storage need. Especially in cases of contradictional requirements for the desired time courses of a dialysis session the used method performs well
Keywords :
blood; electrolytes; optimisation; patient treatment; blood filtration; dialysis session desired time courses; efficient algorithm; individually optimized dialysis profiles design; modified continuous descent procedure; optimal electrolyte concentrations computation; patient status; unconstrained static minimization theory; Algorithm design and analysis; Biomedical computing; Biomedical engineering; Blood; Design optimization; Mathematics; Medical treatment; Open loop systems; Optimal control; Trajectory;
Conference_Titel :
Engineering in Medicine and Biology Society, 1996. Bridging Disciplines for Biomedicine. Proceedings of the 18th Annual International Conference of the IEEE
Conference_Location :
Amsterdam
Print_ISBN :
0-7803-3811-1
DOI :
10.1109/IEMBS.1996.646265
