Notice of RetractionToxic Effects of Nano-Fe2O3 on Liver and Kidney Cells of Rats

Notice of Retraction

After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.

We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.

The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.

In order to assess the toxic effects of nano-Fe₂O₃ on organisms, in the present study, the liver and kidney cells of rats were exposed to different concentrations (0.05, 0.50, 5.00, 50.00 μg/mL) of nano-Fe₂O₃ at 37°C for one hour. Then reactive oxygen species (ROS) levels, glutathione (GSH) contents and DNA protein crosslinks (DPC) coefficients were detected. The results showed that nano-Fe₂O₃ exposure significantly decreased GSH contents, increased the levels of ROS, as well as DPC coefficients. Compared with control group, under 0.05 μg/mL and 0.50 μg/mL nano-Fe₂O₃ exposure, the increase levels of ROS and decrease contents of GSH were not significant difference (p>;0.05). With the exposure concentration increased, 5.00 μg/mL and 50.00 μg/mL nano-Fe₂O₃ concentration groups, the increase levels of ROS and decrease contents of GSH showed significant difference (p<;0.05 or p<;0.01), and demonstrated a certain degree of dose dependent relationship. The increase of DPC coefficients showed significant difference (p<;0.05 or p<;0.01) at 0.50 μg/mL and 5.00 μg/mL concentration group while no significant difference (p>;0.05) was found at 0.05 μg/mL concentration group. This study demonstrates that nano-Fe₂O₃ exposure can produce oxidative stress in the liver and kidney cells of rats.