Title :
Notice of Retraction
Human Osteosarcoma Cell Functions Enhanced by Nanoscale TiO2 with Different Surface Topography
Author :
Xiaoling Xiang ; Mingdi Jiang ; Bing Han ; Liting Yao ; Zhihong Zhu ; Xu Yang
Author_Institution :
Hubei Key Lab. of Genetic Regul. & Integrative Biol., Huazhong Normal Univ., Wuhan, China
Abstract :
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
Three types of titanium (Ti) based nanoscale titania (TiO2) were produced by controlling the reaction conditions, including TiO2 nanotubes, TiO2 nanonetworks and TiO2 nanoparticles. Human Osteosarcoma cells (MG63) were used in this study to evaluate the bioactivity and cytocompatibility of the new materials. Compared to flat Ti, cell adhesion of the materials coated with nanoscale TiO2 was significantly enhanced after 2h, 24h, and 72 h of co-incubation, according to SEM photographs. More importantly, compare to the control group, the lactate dehydrogenase (LDH) released into the culture media and the absorbance of MTT showed no obvious difference after 72 h of co-incubation. Therefore, it is suggested that nanoscale TiO2 is a bioactive and cytocompatible biomedical material.
Keywords :
adhesion; biochemistry; biological specimen preparation; biomechanics; biomedical materials; bone; cancer; cellular biophysics; nanomedicine; nanoparticles; nanotubes; sorption; titanium compounds; MG63 cells; MTT absorbance; SEM; TiO2; bioactivity; cell adhesion; culture media; cytocompatible biomedical material; human osteosarcoma cell functions; lactate dehydrogenase; nanoparticles; nanotubes; reaction conditions; surface topography; time 2 h to 72 h; titanium based nanoscale titania; Adhesives; Bones; Materials; Nanoparticles; Nanoscale devices; Nanotubes; Surface topography;
Conference_Titel :
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-5088-6
DOI :
10.1109/icbbe.2011.5781373
