Notice of RetractionEffects of MnO2 Nanoparticles on Liver and Kidney Cells of Rats

Notice of Retraction

After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.

We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.

The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.

In order to study the effects of MnO₂ nanoparticles on cells of rats liver and kidney, rats liver and kidney cells were exposed to different concentrations (0, 0.05, 0.50, 5.00, 50.00 μg/mL) of MnO₂ nanoparticles at 37°C. An hour later, reactive oxygen species (ROS) levels, glutathione (GSH) concentrations and DNA-protein crosslinks (DPC) degrees in cells were measured to detect the adverse effects. Results showed that compared with the control group, under the 0.5 μg/mL MnO₂ nanoparticles exposure, neither the concentrations of GSH reduce nor the levels of ROS increase significantly (p>;0.05), but the increase of DPC degrees in cells is significant (p<;0.05). There were very significant differences (p<;0.01) in the levels of ROS and DPC degrees in cells in the high concentration groups (5.00 μg/mL), while the concentrations of GSH decrease is very significant in the higher groups (50.00 μg/mL). The results suggest that the low concentrations MnO₂ nanoparticles (≤0.5 μg/mL) have relatively good biocompatibility, manifesting that MnO₂ nanoparticles may be applicable in the rechargeable batteries areas and other related fields.