DocumentCode
3343556
Title
Notice of Retraction
Detection of Formaldehyde Content in Mice Blood after Formaldehyde, Methanol, Formic Acid and Acetaldehyde Exposure
Author
Xiaodan Qin ; Yujie Ke ; Juan Du ; Ren Li ; Shumao Ding
Author_Institution
Hubei Key Lab. of Genetic Regul. & Integrative Biol., Huazhong Normal Univ., Wuhan, China
fYear
2011
fDate
10-12 May 2011
Firstpage
1
Lastpage
4
Abstract
Notice of Retraction
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
In this study, normal saline, formaldehyde, acetaldehyde, methanol and formic acid with the same concentration(20 mg/kg) was gavaged in mice in order to detect these substances toxicity. After the contamination phase, we detected formaldehyde content of all mice´s blood in different contamination groups by AHMT method. The results showed that the formaldehyde content in formaldehyde group and normal saline group was barely changeful, then the methanol group and formic acid group had a little changes compared with formaldehyde group. So it indicated that formaldehyde from outside can not change the level of formaldehyde in mice blood. Then, there might be some enzyme such as formaldehyde dehydrogenase conversing them through metabolic pathway. The detection of DPC ratio in liver organ after 6-day contamination showed that four toxic groups had similar values, which almost remain in the range of 15 %-18 %. The control´s DPC ratio is 6%.
After careful and considered review of the content of this paper by a duly constituted expert committee, this paper has been found to be in violation of IEEE´s Publication Principles.
We hereby retract the content of this paper. Reasonable effort should be made to remove all past references to this paper.
The presenting author of this paper has the option to appeal this decision by contacting TPII@ieee.org.
In this study, normal saline, formaldehyde, acetaldehyde, methanol and formic acid with the same concentration(20 mg/kg) was gavaged in mice in order to detect these substances toxicity. After the contamination phase, we detected formaldehyde content of all mice´s blood in different contamination groups by AHMT method. The results showed that the formaldehyde content in formaldehyde group and normal saline group was barely changeful, then the methanol group and formic acid group had a little changes compared with formaldehyde group. So it indicated that formaldehyde from outside can not change the level of formaldehyde in mice blood. Then, there might be some enzyme such as formaldehyde dehydrogenase conversing them through metabolic pathway. The detection of DPC ratio in liver organ after 6-day contamination showed that four toxic groups had similar values, which almost remain in the range of 15 %-18 %. The control´s DPC ratio is 6%.
Keywords
biochemistry; biological techniques; blood; cellular biophysics; chemical hazards; contamination; enzymes; molecular biophysics; organic compounds; toxicology; AHMT method; acetaldehyde exposure; contamination phase; enzyme; formaldehyde content detection; formaldehyde dehydrogenase; formaldehyde exposure; formic acid exposure; metabolic effect; methanol exposure; mice blood; traditional toxic substance; Blood; Contamination; DNA; Electron tubes; Humans; Methanol; Mice;
fLanguage
English
Publisher
ieee
Conference_Titel
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location
Wuhan
ISSN
2151-7614
Print_ISBN
978-1-4244-5088-6
Type
conf
DOI
10.1109/icbbe.2011.5781410
Filename
5781410
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