Title :
DNA Biosensor Based on the CdS Modified Glassy Carbon Electrode
Author :
Xu, Laihui ; Lu, Liping ; Gao, Zhao ; Kang, Tianfang ; Cheng, Shuiyuan
Author_Institution :
Coll. of Enviromental & Energy Eng., Beijing Univ. of Technol., Beijing, China
Abstract :
An electrochemical sensor for DNA hybridization detection using methylene blue (MB) as indicator was developed. CdS nanoparticals were electrodeposited on the glassy carbon electrode (GCE). DNA probe and the CdS was linked by cysteine. The electrochemical response of the DNA hybridization was measured by differential pulse voltammetry (DPV). The differ ence of the cathodic peak currents of MB after the hybridization of the DNA probe was obvious. In addition, the morphology of the modified electrode was characterized by AFM.
Keywords :
DNA; II-VI semiconductors; atomic force microscopy; biochemistry; biological techniques; biosensors; cadmium compounds; electrodeposition; molecular biophysics; nanoparticles; nanosensors; voltammetry (chemical analysis); AFM; C; CdS; DNA biosensor; DNA hybridization; DNA hybridization detection; DNA probe; cysteine; differential pulse voltammetry; electrochemical analysis; electrochemical sensor; electrodeposition; glassy carbon electrode; methylene blue; nanoparticals; Biosensors; DNA; Electrodes; Morphology; Nanoparticles; Probes; Surface morphology;
Conference_Titel :
Bioinformatics and Biomedical Engineering, (iCBBE) 2011 5th International Conference on
Conference_Location :
Wuhan
Print_ISBN :
978-1-4244-5088-6
DOI :
10.1109/icbbe.2011.5781421
