A resting-state fMRI study of patients with HIV infection based on regional homogeneity method

Author

Wenjuan Qiu ; Bin Yan ; Jianxin Li ; Li Tong ; Ling Wang ; Dapeng Shi

Author_Institution

Nat. Digital Switching Syst. Eng. & Technol. Res. Center, Zhengzhou, China

Volume

2

fYear

2011

fDate

26-28 July 2011

Firstpage

997

Lastpage

1000

Abstract

In this study, the Regional Homogeneity (ReHo) approach was used to investigate the abnormal brain areas in individuals infected with Human Immunodeficiency Virus (HIV) compared with the controls, on the resting state with fMRI. Significantly decreased brain regions were found at multiple brain locations. However, no increased brain region appeared. These detected differences provided additional imaging evidence that HIV virus could cause serious damage to the human nervous system and cognitive abnormalities commonly occur in patients with HIV infection.

Keywords

biomedical MRI; brain; cognition; diseases; medical image processing; neurophysiology; patient diagnosis; HIV infection; abnormal brain areas; brain locations; cognitive abnormalities; human immunodeficiency virus; human nervous system; regional homogeneity method; resting-state fMRI; Acquired immune deficiency syndrome; Brain; Dementia; Human immunodeficiency virus; Magnetic resonance imaging; HIV; Regional Homogeneity; Resting-state; fMRI;

fLanguage

English

Publisher

ieee

Conference_Titel

Natural Computation (ICNC), 2011 Seventh International Conference on

Conference_Location

Shanghai

ISSN

2157-9555

Print_ISBN

978-1-4244-9950-2

Type

conf

DOI

10.1109/ICNC.2011.6022180

Filename

6022180