Title :
Spectroscopic optical coherence tomography
Author :
Morgner, U. ; Drexler, Wolfgang ; Li, Xin ; Kartner, Franz X. ; Pitris, C. ; Boppart, Stephen A. ; Ippen, Erich P ; Fujimoto, J.G.
Author_Institution :
Dept. of Electr. Eng. & Comput. Sci., MIT, Cambridge, MA, USA
Abstract :
Summary form only given. Optical coherence tomography (OCT) has recently emerged as a powerful imaging technique for biological tissue. OCT can perform real time, in situ imaging of tissue cross-sectional microstructure with micron resolution. The spatial resolution of OCT depends directly on the optical bandwidth and thus on the coherence length of the used light source. Using a femtosecond mode-locked Ti:sapphire laser as a low coherence source, in-vivo imaging of biological tissue has been demonstrated with a spatial resolution below 2 /spl mu/m. We report a spectroscopic OCT approach which detects the full interferometric fringe signal and extracts spectroscopic data from the measurement using Fourier signal processing.
Keywords :
Fourier transform optics; Fourier transform spectroscopy; bio-optics; biological tissues; high-speed optical techniques; laser applications in medicine; light coherence; light interferometry; medical image processing; optical tomography; Fourier signal processing; Michelson interferometer; biological tissue imaging; coherence length; femtosecond mode-locked Ti:sapphire laser; full interferometric fringe signal; in-vivo imaging; living tadpole; low coherence source; real time in situ imaging; spatial resolution; spectroscopic optical coherence tomography; stepwise FT; tissue cross-sectional microstructure; Biological tissues; Biomedical optical imaging; Coherence; Optical imaging; Optical interferometry; Optical signal processing; Spatial resolution; Spectroscopy; Tomography; Ultrafast optics;
Conference_Titel :
Quantum Electronics and Laser Science Conference, 1999. QELS '99. Technical Digest. Summaries of Papers Presented at the
Conference_Location :
Baltimore, MD, USA
Print_ISBN :
1-55752-576-X
DOI :
10.1109/QELS.1999.807300